Development of optimal management of upper gastrointestinal bleeding secondary to pancreatic sinistral portal hyper-tension

VernacularTitle:胰源性门静脉高压症合并上消化道出血的治疗策略
Author: Yang SONG ; Hao LU ; Quanda LIU
Publication Type:Journal Article
Keywords: pancreatic diseases; hypertension,portal; gastrointestinal hemorrhage; esophageal and gastic varices; venous thrombeoembo-lism; review
From: Journal of Clinical Hepatology 2014;30(8):740-742
CountryChina
Language:Chinese
Abstract: The pathogenesis of pancreatic sinistral portal hypertension (PSPH)is quite different from that of cirrhotic portal hypertension, and PSPH is the only curable type of portal hypertension.Gastric variceal bleeding is a less common manifestation of PSPH;however,it probably exacerbates the patient’s condition and leads to critical illness,and inappropriate management would result in death.Therefore,it is necessary to develop the optimal management of upper gastrointestinal bleeding in PSPH patients.Splenectomy is considered as a definitive procedure,together with surgical procedures to treat underlying pancreatic diseases.For patients in poor conditions or ineligible for surgery, splenic artery coil embolization is a preferable and effective method to stop bleeding before second-stage operation.The therapeutic decision should be made individually,and the further multi-center study to optimize the management of upper gastrointestinal bleeding from PSPH is warranted.