Application of metabolomics in research on biomarkers for hepatocellular carcinoma
10.3969/j.issn.1001-5256.2014.08.039
- VernacularTitle:代谢组学在肝细胞癌标志物研究中的应用
- Author:
Jiangang WANG
;
Huacheng LI
;
Xinying FEI
- Publication Type:Journal Article
- Keywords:
carcinoma;
hepatocellular;
tumor markers;
biological;
alpha-fetoproteins
- From:
Journal of Clinical Hepatology
2014;30(8):838-840
- CountryChina
- Language:Chinese
-
Abstract:
As a novel research tool,metabolomics technology can reveal the differences in metabolic profiles during the development and progression of hepatocellular carcinoma (HCC),so it has been widely applied for research on HCC biomarkers.The significance of metabo-lomics in the diagnosis of HCC is briefly described,and the metabolomics research aiming at the discovery of HCC biomarkers,including an-imal experiments and clinical studies of metabolites in the serum,urine,and liver tissue,is reviewed.It is pointed out that analyzing and monitoring metabolites in the development and progression of HCC is of great significance for individualized treatment.
