Research advances in molecular prediction of recurrence and metastasis of primary liver cancer after liver transplan-tation
10.3969/j.issn.1001-5256.2014.12.032
- VernacularTitle:预测原发性肝癌肝移植术后复发转移的分子标志物研究进展
- Author:
Man CHEN
;
Xia ZHANG
- Publication Type:Journal Article
- Keywords:
liver neoplasms;
liver transplantation;
neoplasm recurrence,local;
neoplasm metastasis;
forecasting;
review
- From:
Journal of Clinical Hepatology
2014;30(12):1361-1365
- CountryChina
- Language:Chinese
-
Abstract:
Liver transplantation is an essential treatment of primary liver cancer,but the postoperative high risk of recurrence and metastasis has seriously affected the effect of liver transplantation.With the development of molecular biology,researchers have found numerous molec-ular markers potentially related to the recurrence and metastasis of liver cancer after liver transplantation.These markers,including genes, proteins,tumor markers,and serum viruses,are summarized,and their predictive values for tumor recurrence and metastasis after liver transplantation are analyzed.A growing number of molecular markers have been found,but which is not enough for clinical guidance.There-fore,more studies are needed to identify appropriate molecular markers of tumor recurrence and metastasis after liver transplantation.
