Application of proteomics in study of hepatocellular carcinoma

VernacularTitle:蛋白质组学研究技术在肝细胞癌诊疗中的应用
Author: Jiangang WANG ; Xinying FEI ; Qing SONG
Publication Type:Journal Article
Keywords: carcinoma,hepatocellular; proteomics; biomarkers,pharmacological; review
From: Journal of Clinical Hepatology 2014;30(9):958-960
CountryChina
Language:Chinese
Abstract: Hepatocellular carcinoma (HCC)is one of the most fatal malignant tumors worldwide.As an important part of cutting-edge re-search fields,proteomics has been widely used in the studies of related diseases and has currently become a crucial experimental approach to research on HCC.Significantly expressed proteins can be identified as potential biomarkers for early diagnosis and targets for therapeutic drugs for HCC.Moreover,they can be used for prediction of the recurrence and prognosis of HCC,as well as for investigation of pathogene-sis of the disease.The proteomic results from worldwide clinical studies of HCC are summarized,and it is suggested that the clinical applica-tion of results of basic research on HCC proteomics will bring great benefit to the diagnosis and treatment of HCC.