Successful Treatment of Recalcitrant Primary Follicular Mucinosis with Indomethacin and Low-dose Intralesional Interferon Alpha.

Author: Kyu Ri KIM ¹ ; Ji Yeoun LEE ; Mi Kyeong KIM ; Tae Young YOON
Author Information

1. Department of Dermatology, School of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Korea. tyyoon@chungbuk.ac.kr
Publication Type:Case Report
Keywords: Follicular mucinosis; Indomethacin; Interferon alpha
MeSH: Hair Follicle; Indomethacin; Interferon-alpha; Interferons; Mucinosis, Follicular; Mucins; Sebaceous Glands
From:Annals of Dermatology 2009;21(3):285-287
CountryRepublic of Korea
Language:English
Abstract: Follicular mucinosis (FM) is an epithelial reaction pattern that is characterized by the accumulation of mucinous material in the epithelial hair follicle sheath and the sebaceous glands. Although various pharmacological agents have been employed in an attempt to treat FM, effective therapeutic options have remained elusive. We experienced a recalcitrant form of primary FM that we successfully treated with indomethacin and low-dose intralesional interferon alpha (IFN alpha), respectively. To the best of our knowledge, the primary type of FM that responded to indomethacin and low-dose IFN alpha, respectively, in a single case has not been reported in the English medical literature.