Changes of Oscillatory Potentials of Electroretinogram after Methanol Intoxication in Rats
10.3969/j.issn.1004-5619.2014.03.005
- VernacularTitle:大鼠甲醇中毒后视网膜电图振荡电位的变化
- Author:
Dongmei LIU
;
Shu ZHOU
;
Jiemin CHEN
;
Shuya PENG
;
Wentao XIA
- Publication Type:Journal Article
- Keywords:
forensic medicine;
poisoning;
methanol;
electroretinogram;
oscillatory potentials;
rats
- From:
Journal of Forensic Medicine
2014;(3):178-180
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the characters of oscillatory potentials (OPs) of electroretinogram (ERG) after methanol intoxication in rats. Method The SD rat models of methanol intoxication were established and divided into control group, 3-day intoxication group, 7-day intoxication group. The changes of OPs of ERG were recorded in a dark room. Results The total amplitudes of 3-day and 7-day intoxication groups decreased approximately 50% compared with that of the control group, while the schedule de-layed approximately 16% and 61%, respectively. Conclusion The characters of methanol intoxication in rats included delay in schedule and decline in the total amplitude of OPs.