Relationship between Genetic Polymorphism of Dopamine Receptor and Schizophrenia and Its Forensic Significance
10.3969/j.issn.1004-5619.2014.03.012
- VernacularTitle:多巴胺受体基因遗传多态性与精神分裂症的关联及法医学意义
- Author:
Jun YAO
;
Baojie WANG
- Publication Type:Journal Article
- Keywords:
forensic psychiatry;
schizophrenia;
review [publication type];
receptors,dopamine;
polymor-phism,genetic
- From:
Journal of Forensic Medicine
2014;(3):202-206
- CountryChina
- Language:Chinese
-
Abstract:
Schizophrenia is a common but complex mental disorder affected by multiple factors. Forensic psychiatric assessment of schizophrenia involves evaluations on many aspects, but there is no effective biological identification index for schizophrenia. Researches indicate that dysfunction of dopaminergic neurotransmission plays an important role in the pathogenesis of schizophrenia. Our study reviews the classification, genetic structure of dopamine receptors and the recent pertinent studies between the dopamine receptors and schizophrenia and its forensic significance.
