Analysis of 59 Anaphylactic Death Cases
10.3969/j.issn.1004-5619.2015.03.009
- VernacularTitle:59例过敏反应死亡案例分析
- Author:
Zhengdong LI
;
Ningguo LIU
;
Ziqin ZHAO
;
Yiwen SHEN
;
Yijiu CHEN
- Publication Type:Journal Article
- Keywords:
forensic pathology;
death;
allergic reaction
- From:
Journal of Forensic Medicine
2015;(3):206-210
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the cases of anaphylactic death cases and explore the standards of judi-cial expertise of anaphylactic death for providing evidence for judicial expertise. Methods Fifty-nine cas-es death due to allergic reaction in Shanghai were collected. And details of medical history, clinical manifestation of anaphylactic reaction and postm ortem exam ination findings were review ed for all cases. Results In the 59 cases, there were 58 cases died from drug allergy, including 77.6% of them were an-tibiotics. The rates of treating in standard hospital and illegal clinic were 37.3% and 61.0%, respectively. The allergic sym ptom s were dyspnea and facial cyanosis. The time from contacting allergens to death ranged from 1 m in to 3 d. The concentration of total serum IgE ranged from 50 to 576.92 IU/m L . The results of clinical manifestation and pathological anatomy had obviously changes. Conclusion B ased on the exclusion of all other cause of death and synthetically analysis of details of cases, medical history, clinical manifestation and anatomy, the conclusion of anaphylactic death can reached. The details of cas-es including clinical history, exposure to allergens, and clinical manifestation play an im portant role in diagnosis of anaphylactic death.