Forensic Investigation of GoldeneyeTM DNA ID 22NC Kit
10.3969/j.issn.1004-5619.2015.04.007
- VernacularTitle:GoldeneyeTM DNA身份鉴定系统22NC试剂盒的法医遗传学调查
- Author:
Yuan LIN
;
Tingzhi QUE
;
Zhenmin ZHAO
;
Suhua ZHANG
- Publication Type:Journal Article
- Keywords:
forensic genetics;
polym orphism,genetics;
short tandem repeat;
G oldeneyeTM DNA ID 22N CKit
- From:
Journal of Forensic Medicine
2015;(4):280-283
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the genetic data of 21 autosom al STR included in G oldeneyeTM DNA ID 22N CK it in Chinese H an nationality and to evaluate the forensic application. Methods B y detected 500 unrelated healthy individuals in Chinese H an nationality of East China w ith G oldeneyeTM DNA ID 22N CK it, allele frequencies, population genetics param eters and linkage disequilibrium inform ation of the 21 autosom al STR w ere statistically analyzed. Results In the 21 autosom al STR , no deviations from H ardy-W einberg equilibrium w ere detected and all loci w ere independent form each other. D P values of 21 au-tosom al STR w ere all above 0.85, and the com bined discrim ination pow er w as 1-3.616 5×10-26. Com bined m ean exclusion chance of this system in duo cases w as 1-2.786 81×10-6, in trio cases w as 1-8.545 82× 10-10. Conclusion Tw enty-one autosom al STR included in G oldeneyeTM DNA ID 22N CK it are highly polym orphic in the H an nationality. Com bined w ith G oldeneyeTM DNA ID 20A K it, the kit can satisfy the needs for full-sibling testing and facilitate the solution of this kind of case tools.
