Current update on combined hepatocellular and cholangiocarcinoma
10.11958/20160019
- VernacularTitle:混合型肝癌的最新研究进展
- Author:
Dongming LIU
;
Lu CHEN
;
Yao TIAN
;
Xihao ZHANG
;
Qiang LI
- Publication Type:Journal Article
- Keywords:
carcinoma,hepatocellular;
bile duct neoplasms;
review;
combined hepatocellular and cholangiocarcinoma
- From:
Tianjin Medical Journal
2016;44(9):1181-1184
- CountryChina
- Language:Chinese
-
Abstract:
Combined hepatocellular and cholangiocarcinoma (HCC-CC) is a rare primary hepatic neoplasm (PHN) with features of both hepatocellular and biliary differentiation. Hepatitis B and hepatitis C are the major causes of HCC-CC. Surgical treatment is the main therapeutic method for HCC-CC. For patients with unresectable lesions, curative or palliative locoregional therapy is applied, including radiofrequency ablation (RFA), transarterial chemoembolization (TACE) and supportive treatment. Because of the rare occurrence and ambiguous clinical features of HCC-CC, it is most often misdiagnosed with the other two types of primary liver cancer. Thus, the realization of the current progress of combined hepatocellular and cholangiocarcinoma is particularly important for us. This article aims to summarize the epidemiology and clinical futures, the treatment and prognosis, the progress of genetics and molecular analysis of HCC-CC.
