Changes of circulating GPC4 levels and its association with HbA1C in subjects with different glucose tolerances
10.3760/cma.j.issn.1000-6699.2016.08.010
- VernacularTitle:不同糖耐量人群中血浆 GPC4水平与 HbA1C 的相关性研究
- Author:
Wenjing HU
;
Dongliang LIU
;
Jie YAO
;
Weiwei SHEN
;
Xiangjun LI
;
Xiaoyun FAN
- Publication Type:Journal Article
- Keywords:
Glypicans 4;
HbA1C;
Diabetes mellitus,type2
- From:
Chinese Journal of Endocrinology and Metabolism
2016;32(8):674-676
- CountryChina
- Language:Chinese
-
Abstract:
[Summary] To evaluate the relationships between plasma GPC4 levels and HbA1C . Plasma GPC4 levels were measured in subjects with different glucose tolerances. The relationship between plasma GPC4 levels and HbA1C were studied. Increasing levels of GPC4 showed a significant linear trend and were independently associated with HbA1C . GPC4 levels gradually declined after gradually increased , which is similar with Fins, 2hIns, and AUCinsulin . GPC4 may be involved in the regulation of blood glucose and GPC4 may be regulated by insulin.