The application of insulin-like growth factors system in the diagnosis and treatment of tumor
10.3760/cma.j.issn.1009-9158.2016.08.004
- VernacularTitle:胰岛素样生长因子系统在肿瘤诊治中的应用
- Author:
Hongmei ZHAO
;
Yanqing WANG
;
Xiaoli WU
;
Xin. GAO
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Somatomedins;
Signal transduction;
Tumor markers,biological
- From:
Chinese Journal of Laboratory Medicine
2016;39(8):575-577
- CountryChina
- Language:Chinese
-
Abstract:
Malignancies threaten human health seriously.Recently studies show that intercellular signal transduction influences the biological characteristics of tumor cells.It has closely relationship with tumor growth and metastasis.Insulin-like growth factor ( IGFs ) signal transduction system is a potential mitogen that distributed in the body′s tissues, organs and blood.Researches show that the abnormal expression of IGFs exists in many tissues, such as breast cancer, colorectal cancer, gastric carcinoma, lung carcinoma, pancreatic cancer and so on, which may play an important role in occurrence and metastasis as a novel tumor marker.
