Research progress on long non-coding RNA in gastric cancer
10.3760/cma.j.issn.1009-9158.2016.08.005
- VernacularTitle:长链非编码 RNA 在胃癌中的研究进展
- Author:
Xi LUO
;
Feng WANG
;
Xianjuan SHEN
;
Shaoqing JU
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
RNA,long noncoding;
Biological markers
- From:
Chinese Journal of Laboratory Medicine
2016;39(8):578-580
- CountryChina
- Language:Chinese
-
Abstract:
Long non-coding RNAs are a novel class of non-protein coding RNA molecules with more than 200 nucleotides in length.Recently, mounting evidence has been demonstrated that lncRNAs play crucial roles in epigenetic modification and gene expression regulation. This review aims to summarize current knowledge of lncRNAs in the carcinogenesis, clinical diagnosis, drug resistance and prognosis prediction of gastric cancer.