Effects of endoscopic ultrasonography combined with fine needle aspiration biopsy on pancreatic cystic lesions
10.3760/cma.j.issn.1007-5232.2016.07.003
- VernacularTitle:内镜超声联合细针穿刺活检术对胰腺囊性病变诊断效果评价
- Author:
Huiyun ZHU
;
Fei JIANG
;
Zhendong JIN
;
Zhaoshen LI
- Publication Type:Journal Article
- Keywords:
Pancreatic neoplasms,cystic;
Endoscopy;
Ultrasonography;
Biopsy,fine-needle;
Diagnosis,differential
- From:
Chinese Journal of Digestive Endoscopy
2016;33(7):433-436
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effects of endoscopic ultrasonography ( EUS) combined with cyst fluid analysis, cytology, histopathology based on endoscopic ultrasound guided fine needle aspiration ( EUS?FNA) on pancreatic cystic lesions ( PCLs) . Methods Clinical data of 45 patients were analyzed ret?rospectively from January 2006 to April 2015 including MRI, EUS?FNA, MRCP. The results of conventional imaging and EUS?FNA were compared based on postoperative pathology. Results There were 8 cases of non tumor pancreatic cystic lesions, 4 cases of serous cystadenoma (SCN), 11 cases of mucinouscystadenoma ( MCN) , 8 cases of intraductal papillary mucinous tumor ( IPMN ) , 5 cases of solid pseudopapillary papilloma ( SPN) , 9 cases of non pancreatic cystic lesions ( nPCLs) . The diagnostic accuracy rate of tradi?tional imaging tests ( B?ultrasound, CT, MRI, MRCP ) and EUS?FNA were 42?2% ( 19/45 ) and 77?8%(35/45) (P<0?05). The diagnostic value of EUS?FNA of PCLs was higher than that of traditional imaging tests, with specificity, sensitivity, positive predictive value ( PPV) and negative predictive value ( NPV) of 58?3% ( 7/12 ) , 97?0% ( 32/33 ) , 86?5%( 32/37 ) , 87?5% ( 7/8 ) and 41?7% ( 5/12 ) , 87?9%(29/33), 80?6% (29/36), 55?6% (5/9),respectively. Conclusion EUS?FNA is more valuable than traditional imaging tests for the diagnosis of PCLs.
