A comparative study on endoscopic and surgical treatment of small rectal neuroendocrinal tumor
10.3760/cma.j.issn.1007-5232.2016.07.006
- VernacularTitle:内镜与外科手术治疗直肠小神经内分泌肿瘤的回顾性对比研究
- Author:
Dongfeng GAO
;
Wenhao LYU
;
Linhui ZHANG
;
Rui HUANG
;
Shaowei YAO
;
Zhiguo LIU
;
Kaichun WU
- Publication Type:Journal Article
- Keywords:
Rectum;
Neuroendocrine tumors;
Laparoscopes;
Surgical procedures,operative;
Endoscopic submucosal dissection
- From:
Chinese Journal of Digestive Endoscopy
2016;33(7):447-450
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the differences between endoscopic resection and laparoscopy?assisted surgery or transanal endoscopic resection for rectal neuroendocrinal tumor. Methods Clinical data of patients who underwent endoscopic or surgical resection of neuroendocrinal tumor of less than 2 cm which were confirmed by pathology from December 2010 to November 2013 were retrospectively analyzed. Results Twenty cases of endoscopic treatment, including 17 cases of ESD, 3 cases of EMR,were included in endoscopy group;while 18 cases treated with surgery were included in surgery group, among which 12 ca?ses underwent transanal endoscopic microsurgery and 6 cases laparoscopic resection. The mean lesion sizes were 7 mm(4?18 mm)and 8 mm(3?15 mm),respectively. Pathology showed there were 16 cases of grade G1 neurocrinal tumor and 2 G2 cases in surgical group. There was no lymphvascular invasion with clear margin in the endoscopy group,but three cases of lymphvascular invasion in surgical group. No treatment?related se?vere adverse event occurred in either group. The time for oral food intake was 2?0 d(1?4 d) in endoscopy group, while that in surgery group was 2?4 d(1?7 d)(P=0?295). The hospital stay was(6?80±2?12) d in endoscopy group and(8?59±2?85)d in surgery group, respectively(P=0?034). And the total hospitalization cost was 10 488(4 128?15 296) yuan and 15 590(3 024?40 503) yuan(P=0?031) in the two groups, re?spectively. The follow?up was 25 months(2?48 months)and no recurrence was found. Conclusion Endo?scopic resection, especially ESD, is a new approach to treat colorectal neuroendocrinal tumor,advantageous over surgery in shorter hospitalization time, minimal invasiveness, faster postoperative recovery, less compli? cation, and reduced hospitalization cost.
