Chemotherapy for infections caused by carbapenem-resistant Gram-negative bacteria
10.3760/cma.j.issn.1674-2397.2016.04.004
- VernacularTitle:碳青霉烯类耐药革兰阴性菌感染的抗菌治疗
- Author:
Junyan QU
;
Xiaoju LYU
- Publication Type:Journal Article
- Keywords:
Carbapenem;
Gram-negative bacteria;
Drug resistance;
Treatment
- From:
Chinese Journal of Clinical Infectious Diseases
2016;9(4):307-313
- CountryChina
- Language:Chinese
-
Abstract:
Gram-negative bacteria are the common pathogens causing nosocomial infections.The drug resistance of gram-negative bacteria has become increasingly serious in last two decades.Carbapenems were once considered as the last line of defense against serious infections of gram-negative pathogens.As carbapenemase-producing strains are spreading, the incidence of infections caused by carbapenem-resistant isolates is increasing worldwide.The pathogens are usually multiple drug resistant strains or extensively drug resistant strains, and effective treatment options are limited, even there are no more drugs in certain conditions.This article focuses on appropriate antibiotics and therapeutic strategies for effective control of infections with carbapenem-resistant gram-negative pathogens.
