Research advances in new anti-HBV targets and related drugs
10.3760/cma.j.issn.1674-2397.2016.04.020
- VernacularTitle:抗乙型肝炎病毒新靶点及相关药物研究进展
- Author:
Qiang LI
;
Qibin ZHUO
;
Yuxian HUANG
;
Liang CHEN
- Publication Type:Journal Article
- Keywords:
Hepatitis B virus;
Antiviral agents;
Target
- From:
Chinese Journal of Clinical Infectious Diseases
2016;9(4):379-384
- CountryChina
- Language:Chinese
-
Abstract:
Interferon and nucleotide/nucleoside analogues are currently widely used in the management of chronic hepatitis B virus ( HBV) infections, but are facing problems such as poor sustained virologic response, low HBsAg clearance rate and a high risk of recurrence after drug withdraw.Exploring new target of anti-HBV agent has become a hot topic in recent years.This paper reviews the research progress on new anti-HBV targets and related drugs.