The role of Cyr61 in tumors and its clinical application
10.3760/cma.j.issn.1009-9158.2016.08.003
- VernacularTitle:Cyr61在肿瘤中的作用及临床应用前景
- Author:
Conglian WU
;
Xianjin ZHU
;
Yingping CAO
- Publication Type:Journal Article
- Keywords:
Neoplasms;
CCN intercellular signaling proteins;
Cysteine-rich protein 61;
Integrins
- From:
Chinese Journal of Laboratory Medicine
2016;39(8):571-574
- CountryChina
- Language:Chinese
-
Abstract:
Cyr61/CCN1 is a secreted extracellular matrix ( ECM) protein, which has been shown to regulate a multitude of cellular responses.Many researches indicate that Cyr61 plays important roles in oncogenesis and development of tumor and is considered to be a novel potential oncogene.This review would provide a comprehensive summary about the roles of Cyr61 in the diagnosis and treatment of tumor.