The application and development of liquid chromatography-mass spectrometry in clinical laboratory medicine
10.3760/cma.j.issn.1009-9158.2016.08.021
- VernacularTitle:液相色谱－质谱联用技术在临床检验中的应用与发展
- Author:
Shaoting WANG
;
Yan LI
- Publication Type:Journal Article
- Keywords:
Chromatography,liquid;
Tandem mass spectrometry;
Metabolism,inborn errors;
Drug monitoring
- From:
Chinese Journal of Laboratory Medicine
2016;39(8):650-653
- CountryChina
- Language:Chinese
-
Abstract:
In the past decade, liquid chromatography-mass spectrometry has undergone rapid development in clinical laboratory medicine.Benefiting from the high sensitivity and specificity, as well as the capability of multi-component analysis in the single run, such technology is regarded as an excellent alternative to conventional immunoassays towards newborn screening for the genetic diseases, therapeutic drug monitoring and endocrine hormones detection.With the continuing progress in expertise-training, quality assurance and methodology standardization, it could be expected that liquid chromatography-mass spectrometry would become a dynamic and crucial part for routine clinical applications in the near future.
