Comparison of clinical effect of erythromycin and azithromycin in the treatment of mycoplasma pneumonia
10.3760/cma.j.issn.1008-6706.2016.19.037
- VernacularTitle:红霉素与阿奇霉素治疗支原体肺炎临床效果比较
- Author:
Haiyan SONG
;
Bin WANG
- Publication Type:Journal Article
- Keywords:
Children;
Mycoplasma pneumonia;
Diagnosis;
Treatment
- From:
Chinese Journal of Primary Medicine and Pharmacy
2016;23(19):3022-3025
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the clinical effect of erythromycin and azithromycin in the treatment of mycoplasma pneumonia.Methods 120 children with mycoplasma pneumonia were randomly divided into study group and control group according to digital table method,60 cases in each group.The control group was treated with erythro-mycin,while the study group used azithromycin treatment.Clinical curative effect was compared between the two groups.Results The disappearing time of cough[(4.58 ±0.75 )d],fever[(4.75 ±1.74)d],pulmonary rales [(7.84 ±2.85)d]of the study group were significantly shorter than those in the control group[(4.58 ±0.75)d, (4.75 ±1.74)d,(7.84 ±2.85)d],and the differences were statistically significant (t =7.54,385,5.93,all P <0.05).The total effective rate in the study group (95.00%)was significantly higher than that in the control group (83.33%),and the difference was statistically significant (χ2 =8.08,P <0.05).There was no significant difference in the incidence of adverse reactions between the study group and the control group (χ2 =0.64,P >0.05 ). Conclusion Mycoplasma pneumonia in children for early diagnosis and treatment of dry,use of azithromycin curative effect was better than that of erythromycin.It could effectively relieve patients of fever,and alleviate the clinical symptoms of cough,pulmonary rales.
