A preliminary study on quality standard and stability forQizhu-Fuzheng Yin

VernacularTitle:芪术扶正饮的质量标准及稳定性初步研究
Author: Xiaoke HAN ; Chaofeng LIANG ; Jun QI
Publication Type:Journal Article
Keywords: Qizhu-Fuzheng Yin; Astragaloside; Chromatography,thin layer; Ultra-performance liquid chromatography-Evaporative light-scattering detector; Quality control
From: International Journal of Traditional Chinese Medicine 2016;38(9):837-840
CountryChina
Language:Chinese
Abstract: Objective To establish the quality standard ofQizhu-Fuzheng Yin, and to conduct a preliminary study on its stability.Methods Corydalis tuber and licorice were identified by TLC. The content of astragaloside was determined by UPLC-ELSD. The initial stability was studied by accelerated test method. Results The spots on TLC plates were clear without interference in the blank reference. The response of astragaloside was linear in the ranges of 36.5-365.0 μg/ml (r2=0.999 2), and the average recovery was 102.8 %, and theRSD was 2.4%. After 1, 2, 3, 6 months tests, the average contents of 3 batches astragaloside were 61.6, 60.4, 60.6μg/ml.ConclusionQizhu-Fuzheng Yin was simple preparation, quality control and stability.