Characteristics and Prognosis in Patients of Acute Coronary Syndrome Combining Anemia After Percutaneous Coronary Intervention
10.3969/j.issn.1000-3614.2016.08.002
- VernacularTitle:急性冠状动脉综合征患者经皮冠状动脉介入治疗术后合并贫血的特点及预后
- Author:
Yang WANG
;
Gong SU
;
Yun ZHOU
;
Guanlin YANG
- Publication Type:Journal Article
- Keywords:
Anemia;
Acute coronary syndrome;
Angioplasty,transluminal,percutaneous coronary;
Prognosis
- From:
Chinese Circulation Journal
2016;31(8):732-736
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the impact of anemia on prognosis for acute coronary syndrome (ACS) patients after percutaneous coronary intervention (PCI). Methods: A total of 220 ACS patients with successful PCI were studied. According to WHO standard, anemia was deifned by HB<130 g/L in male, HB<120 g/L in female, the patients were divided into 2 groups: Anemia group,n=56 and Non-anemia group, n=164, clinical condition was followed-up for 1 year to record the incidence of major adverse cardiac events ( MACE); based on MACE incidence, the patients were divided into another 2 groups: MACE group,n=61, Non-MACE group,n=159, clinical condition with relevant risk factors were analyzed and compared between 2 groups. Results: The patients’ mean age was at (62.39 ± 10.17) years, the ratio of anemia was 26.8% (56/220). Compared with Non-anemia group, the patients in Anemia group had more female gender and 3-vessel disease, higher Gensini score and MACE incidence; while decreased eGFR, lower levels of TC, TG and lower ratios of hypertension and smoking, allP<0.05. Compared with Non-MACE group, the patients in MACE group had the elder age, higher occurrence rates of anemia, diabetes, left ventricular dysfunction (LVEF<50%) and decreased eGFR, allP<0.05-0.001. Logistic analysis indicated that anemia (OR=2.507, 95% CI 1.012-6.208,P=0.047) was the independent risk factors for MACE occurrence in ACS patients at 1 year after PCI. Conclusion: ACS patients combining anemia had the higher incidence of MACE, anemia was the independent risk factor for poor prognosis in ACS patients after PCI.
