Research progress of B vitamins and diabetic nephropathy

VernacularTitle:B族维生素与糖尿病肾病的研究进展
Author: Huanzhen CHEN ; Dongmei TIAN
Publication Type:Journal Article
Keywords: Diabetic nephropathy; B-vitamin; Advanced glycation end products
From: Clinical Medicine of China 2016;32(9):855-858
CountryChina
Language:Chinese
Abstract: Diabetic nephropathy( DN) is one of the main manifestations of diabetic microvascular dis?ease,and it is a major factor in the death of diabetes.At present,the treatment of DN is mainly focused on the control of high blood sugar and high blood pressure.Although angiotensin converting enzyme inhibitors and angio?tensin II receptor antagonists can slow the progression of DN,there were a lot of patients deteriorate to renal fail?ure.The role of vitamin B supplementation in preventing microvascular complications of diabetes has already been a focus of research for some years.In this paper,the role of B vitamins in the pathogenesis of diabetes mellitus and DN,effect of vitamin B supplementation on treatment in DN were discussed.