Analysis on characteristics and drug resistance of pathogens in ICU elderly patients with respiratory tract infection
10.3969/j.issn.1673-4130.2016.16.012
- VernacularTitle:老年危重症监护病区患者呼吸道感染病原菌特点与耐药性分析
- Author:
Lian CHEN
;
Yue ZHAO
;
Fanghua QIU
;
Bixia ZENG
;
Li XI
- Publication Type:Journal Article
- Keywords:
elderly patients;
ICU;
respiratory tract infection;
drug resistance;
multi-drug resistant organism
- From:
International Journal of Laboratory Medicine
2016;37(16):2236-2238
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the distribution characteristic and drug resistance of respiratory tract pathogens in ICU eld‐erly patients to provide the basis for clinical medication and control of nosocomial infection .Methods The isolation situation and drug resistance of pathogens in ICU elderly patients with respiratory tract infection from January 2012 to December 2014 were ret‐rospectively analyzed .Results Among 501 cases of respiratory tract infection ,350 cases were Gram‐negative bacilli infection ,which were mainly P .aeruginosa and A .baumannii;50 cases were Gram‐positive coccus infection ,which was mainly S .aureus ;101 cases were complicating fungal infection ,which was mainly C .albicans .The resistance of P .aeruginosa to imipenem showed upward trend (P<0 .05) ,A .baumannii had higher resistance to commonly used antimicrobial drugs ,but the drug resistance trend had no obvious change(P>0 .05) .Imipenem‐resistant A .bauman(IRAB) ,ESBLs‐producing E .coli and methicillin‐resistant S .aureus (MRSA) in the elderly patients with respiratory tract infection all exceeded 50% of each constitution ratio .Conclusion Multi‐drug resistant bacteria are usually isolated from ICU elderly patients ,their drug resistance rates maintain a higher level .Therefore clinicians should rationally select antibacterial drugs by combining with the laboratory reports ,increase the prevention and management of multi‐drug resistant bacteria and reduce the nosocomial infection occurrence .
