Clinical Observation for Combination of Umbilical Compress Therapy with Xiaotan Lishui ;Gel and Intraperitoneal Chemotherapy with Cisplatin for Gastric Cancer Ascites
10.3969/j.issn.1005-5304.2016.09.009
- VernacularTitle:消痰利水凝胶敷脐联合顺铂腹腔灌注治疗胃癌腹水临床观察
- Author:
Jun SHI
;
Qi JIN
;
Pinkang WEI
- Publication Type:Journal Article
- Keywords:
therapy based on Xiaotan Lishui Gel;
external treatment;
gastric cancer;
ascites
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2016;23(9):36-40
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical efficacy of combination of umbilical compress therapy with Xiaotan Lishui Gel and intraperitoneal chemotherapy with cisplatin in patients with gastric cancer ascites. Methods A total of 78 patients were included and divided randomly into treatment group (39 patients) and control group (38 patients). Patients of both groups received intraperitoneal chemotherapy with cisplatin, and the treatment group received additionally umbilical compress therapy of Xiaotan Lishui Gel. Two weeks were regarded as a course of treatment. All patients were followed up for 180 days. The total effective rate, puncture-free survival, interval time of puncture, median survival time, life quality, improvement of symptoms and safety of the two groups were observed. Results Finally 73 patients completed the observation. The total effective rate was 56.76%(21/37) in the treatment group and 33.33%(12/36) in the control group, with statistical significance (P=0.044). The puncture-free survival and interval time of puncture were 59 d and 62 d, respectively, and 49 d and 54 d in the control group, respectively (P<0.05). There was no difference in median survival time between the two groups. Karnofsky performance status in the treatment group was significantly higher than the control group (P=0.012), and decreased mobility, abdominal pain, abdominal distension, early satiety and urinary frequency in the treatment group were better improved than the control group (P<0.05). Conclusion Combination of umbilical compress therapy with Xiaotan Lishui Gel and intraperitoneal chemotherapy with cisplatin can postpone the ascites increasing speed of patients with gastric cancer ascites, and improve patients’ life quality.
