Histopathological features and prognostic analysis in endoscopic stripping microflap excision of vocal cords ;leukoplakia
10.3760/cma.j.issn.1008-6706.2016.18.001
- VernacularTitle:声带白斑病理特征与内镜下黏膜剥脱术预后分析
- Author:
Wenbin WANG
;
Renjie SU
;
Qianhua PENG
;
Zhengbiao YING
- Publication Type:Journal Article
- Keywords:
Leukoplakia,vocal cord;
Histopathological feature;
Recurrence;
Carcinogenesis
- From:
Chinese Journal of Primary Medicine and Pharmacy
2016;23(18):2721-2723
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the pathological features and prognostic analysis in endoscopic strip-ping microflap excision of vocal cords leukoplakia.Methods A total of 186 cases with vocal cord leukoplakia and treated by endoscopic stripping microflap excision were retrospectively analyzed,calculated the ratios of recurrence and malignant transformation on keratosis without dysplasia,mild dysplasia,moderate dysplasia and severe dysplasia and carcinoma in situ.Then,the association of histopathological classification with recurrence and malignant transformation in vocal cord leukoplakia were evaluated.Results 87 cases of all 186 patients with vocal cord leukoplakia were kera-tosis without dysplasia,17 cases were recurrenced and 3 cases were developed to carcinoma;64 cases were mild dysplasia,15 cases were recurrenced and 7 cases were developed to carcinoma;29 cases were moderate dysplasia, 13 cases were recurrenced and 10 cases were developed to carcinoma;6 cases were severe dysplasia and carcinoma in situ,all 6 cases were recurrenced and 5 cases were developed to carcinoma.Conclusion The histopathological classi-fication is predictive factor for the risk of recurrence and malignant transformation in vocal cord leukoplakia.
