Effect of stomach dampness decoction combined with quadruple therapy on Helicobacter pylori associated ;peptic ulcer

VernacularTitle:和胃化湿汤联合四联疗法治疗幽门螺杆菌相关性消化性溃疡的效果观察
Author: Jiaxin LIU ; Dongbing LIU ; Dongze QIU
Publication Type:Journal Article
Keywords: Peptic ulcer; Helicobacter pylori; Drug therapy,combination; Hewei huashi decoction
From: Chinese Journal of Primary Medicine and Pharmacy 2016;23(18):2757-2759
CountryChina
Language:Chinese
Abstract: Objective To observe the clinical curative effect of stomach dampness decoction combined with quadruple therapy in the treatment of Hp related peptic ulcer.Methods 80 cases of Hp related peptic ulcer were randomly divided into control group and treatment group,40 cases in each group.The control group was treated with quadruple therapy(oral amoxicillin capsule,left ofloxacin tablets,pantoprazole enteric coated tablets,citric acid bis-muth potassium granule),the treatment group was given stomach dampness soup on the basis of the control group.The treatment course was 14 days,1 month after anti Hp therapy,assessed HP eradication rate of the two groups.Results The Hp eradication rate of the treatment group was 95% which was higher than 80% of the control group,the differ-ence was statistically significant(χ2 =4.114,P <0.05).Conclusion Hewei huashi decoction combined with quad-ruple therapy in treating Hp -related petic ulcer has better Hp eradication rate and drug safety than the quadruple therapy.