Effect of edaravone combined with batroxobin in treatment of acute progressive cerebral infarction

VernacularTitle:依达拉奉联合巴曲酶治疗急性进展性脑梗死的疗效观察
Author: Huijuan XU ; Hong LUO ; Jiale DAI
Publication Type:Journal Article
Keywords: Edaravone; Batroxobin; Cerebral infarction
From: Chinese Journal of Primary Medicine and Pharmacy 2016;23(18):2821-2824
CountryChina
Language:Chinese
Abstract: Objective To discuss the efficacy of edaravone combined with batroxobin in the treatment of patients with acute progressive infarction,and its influence on neurological deficit and coagulation.Methods 64 patients with acute and progressive infarction were selected,they were randomly divided into the control group and the observation group,32 cases in each group.The patients of the observation group were given edaravone combined with batroxobin,while the patients of the control group were given batroxobin only.Results The total effective rate of the observation group was 91.63%,which was obviously higher than 78.13% of the control group(χ2 =11.274,P <0.05).The NDS of the observation group was (14.8 ±2.9 )points,which was obviously lower than (17.9 ± 3.3)points of the control group(t =9.98,P <0.05).The level of Fib of the observation group was (2.9 ±0.3)g/L, which was obviously lower than (3.2 ±0.4)g/L of the control group(t =9.34,P <0.05).Conclusion Edaravone combined with batroxobin in the treatment of patients with acute and progressive infarction has significant effect and deserve promotion.