The role of low dose CT as part of the same 18F-NaF PET/CT in detecting bone metastases in lung cancer
10.3969/j.issn.1006-5725.2016.16.029
- VernacularTitle:低剂量CT在18F-NaF PET/CT评价肺癌骨转移中的价值
- Author:
Junqi WANG
;
Shuo GAO
;
Yansheng LI
- Publication Type:Journal Article
- Keywords:
Low dose CT;
Bone metastases;
PET/CT;
18F-NaF;
Lung cancer
- From:
The Journal of Practical Medicine
2016;32(16):2695-2698
- CountryChina
- Language:Chinese
-
Abstract:
Objective Retrospectively evaluate low dose computed tomography (CT) as part of a combined 18F-NaF positron emission tomography (18F-NaFPET/CT) examination in lung cancer patients suspected of bone metastases. Methods 118 of 122 lesions with increased uptake of 18F-NaF were assessed. Characteristics of bone metastases on CT images were reviewed by radiologists. Results 27 of 47 metastases presented as sites of increased uptake with corresponding lytic or sclerotic changes on low dose CT. Other 20 show normal or non-specific appearing bone on CT. Most benign lesions (67 of 71,94%)have a benign appearance on low-dose CT. Conclusions Low dose CT images were useful in precisely diagnosing bone metastasis. Negative low dose CT appearance to the abnormal foci on PET may be a reliable sign of metastases.