Association of serum uric acid level with the prevalence of metabolic syndrome
10.3969/j.issn.1006-5725.2016.15.042
- VernacularTitle:兰州地区不同尿酸水平与代谢综合征的患病率及其关系
- Author:
Yanjia XU
;
Jing LIU
;
Qi ZHANG
;
Mao LI
;
Limin TIAN
;
Jinxing QUAN
- Publication Type:Journal Article
- Keywords:
Uric acid;
Metabolic syndrome;
Prevalence
- From:
The Journal of Practical Medicine
2016;32(15):2556-2559
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation of serum uric acid (SUA) level with the prevalence of metabolic syndrome (MS). Methods A random, multi-stage cross-sectional study was performed in 2364 resuden, aged from 20 to 74, in Lanzhou, Gansu province.The resudents were divided into groups according to the level of SUA or 4 components of MS. The relationship between SUA and MS was analyzed. Results The overall morbidity of MS was 20.13 % in Lanzhou , and the morbidity of MS was higher in female than that in male (23.22% vs. 17.37%, P < 0.05);The prevalences of MS was higher in the hyperuricemia (HUA) people than that in the healthy people (32.40 % vs. 17.70 %,P < 0.05); With the increase of SUA level, the morbidity rates of MS and its components increased;The risk of MS showed a gradual increase with the SUA level, the risk of MS(odds ratio,95%CI)in sex-specific quartiles of SUA was 2.33(1.45 ~ 3.71),2.33(1.45 ~3.71),2.44(1.53 ~ 3.89)in male;and 1.58(0.97~2.56),2.54(1.60 ~ 4.00),5.29(3.41 ~ 8.22)in female. The more the components of MS , the higher the SUA level was found for both the male and the female subjects , with the higher rate of HUA morbidity(P < 0.05). Conclusion There is a significant association between SUA level and MS, as well as the MS components. Comprehensive prevention and control should be taken for the reduction of the risk factors, and much attention should be paid to monitor the SUA level.
