The Application of two Endometrial Mechanical Stimulation Methods in Patients with Repeated Implantation Failure
10.3969/j.issn.1006-5725.2016.16.025
- VernacularTitle:两种机械刺激子宫内膜方法对反复着床失败患者妊娠结局的影响
- Author:
Liman WANG
;
Jiana YAO
- Publication Type:Journal Article
- Keywords:
Endometrial scratching;
Mechanical stimulation;
In vitro fertilization-Embryo transfer;
Repeated implantation failure
- From:
The Journal of Practical Medicine
2016;32(16):2683-2685
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical application of two endometrial mechanical stimulation methods in patients with repeated implantation failure (RIF) in frozen-thawed embryo transfer (FET) cycle. Methods A total of 127 women with RIF who planned to perform FET again were included. They were separated into 3 groups: Group A (45 cases) with endometrial scratching and group B (42 cycles) with endometrial sucking within menstrual period in FET cycle, while in control group C (40 cases), no endometrial mechanical stimulation was performed. The outcomes of pregnancy were compared. Results The endometrial types of endometrial scratching group were mainly type A. The embryo implantation rate and clinical pregnancy rate in group A (27.27%, 46.67%) were significantly higher than those in group B (12.75 %, 21.43%) and group C (11.46%, 20.0%) (P <0.05). Conclusion The endometrial mechanical stimulation can improve the endometrial receptivity, compare with endometrial sucking, endometrial scratching can improve the clinical pregnancy rate of RIF patients more obviously.