Effect of the silver needle injection therapy on rat with Sports muscle injury
10.3969/j.issn.1006-5725.2016.15.008
- VernacularTitle:银质针对大鼠运动性肌损伤疗效观察
- Author:
Ling MA
;
Zishan JIA
;
Hongyu XIAO
;
Lining ZHANG
- Publication Type:Journal Article
- Keywords:
Silver needle;
Sports muscle injury;
Rat
- From:
The Journal of Practical Medicine
2016;32(15):2448-2451
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of silver needle injection therapy on rat with sports muscle injury. Methods Twenty-one healthy male Wistar rats were randomly divided into the injury group (n = 3),the silver needle group (n=12) and the control group (n=3). The expressions of bFGF and GDNF in gastrocnemius muscle tendon junction were detected on 7 d ,14 d and 28 d post-injury. Results No significant difference in the appearance of the injured tissue was found in both two groups on 7 d post-injury. The appearance of the injured tissue was better in the silver needle group than that in the control group on 14 d and 28 d post-injury. The tissue was almost normal in the therapy group on 28 d post-injury; The expression of bFGF in the therapy group was higher than that in the injury control group on 7 d and 14 d post-injury (P < 0.01). The expression of bFGF markedly decreased in the therapy group compared with the control group (P < 0.01) on 28 d post-injury. The expression of GDNF in the therapy group was higher than that in the injury control group on 7 d ,14 d and 28 d post-injury (P<0.01). Conclusion The silver needle injection therapy has the therapeutic effect on sports muscle injury reparation, which can increase the expression of bFGF and GDNF efficiently.