Human papillomavirus genotype in cervical intraepithelial neoplasia grade Ⅱ/Ⅲ and cervical carcinoma:a comparative study
10.3969/j.issn.1006-5725.2016.15.023
- VernacularTitle:宫颈上皮内瘤变Ⅱ／Ⅲ级及宫颈癌中人乳头瘤病毒基因型分布的比较
- Author:
Xiaolin LI
;
Xiaojie WAN
;
Feiyun ZHENG
;
Xuejie ZHU
;
Jianqin YU
- Publication Type:Journal Article
- Keywords:
Cervical Intraepithelial Neoplasia;
Cervical Carcinoma;
Human Papillomavirus;
Genotyping assay
- From:
The Journal of Practical Medicine
2016;32(15):2494-2497
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the distributions of genotypes of HPV infection in CIN and cervical carcinoma. Methods Cervical exfoliated cells were collected from 365 patients with abnormal cervical histology , and subjected to genotyping assay. Results The most prevalent HPV types were 16, 18,52, 58 and 33. The prevalence ratio of HPV 33,52,58 was signi cantly lower in squamous cell carcinoma. Multiple infections decreased from CIN II/III to cervical cancer. Conclusion Besides HPV 16/18, the 52/58/33 subtypes are also important in the development of cervical cancer.
