Progress on Molecular Mechanism of Phosphorylation/Dephosphorylation and Detection Technology of γH2 AX
10.11895/j.issn.0253-3820.160054
- VernacularTitle:γH2 AX磷酸化/去磷酸化的分子机制及检测技术进展
- Author:
Sen ZHANG
;
Lujuan LIU
;
Huan CHEN
;
Hongwei HOU
;
Qingyuan HU
- Publication Type:Journal Article
- Keywords:
γH2 AX;
Phosphorylation;
Immunofluorescence technology;
Toxicity evaluation;
Review
- From:
Chinese Journal of Analytical Chemistry
2016;(8):1291-1299
- CountryChina
- Language:Chinese
-
Abstract:
Since γH2 AX was firstly found in 1998 , it has been one of the most important scientific topics and research tools in the related scientific fields. At present, a series of advanced testing methods and analytical technologies have been developed, which exhibited a quite attractive application prospect in the area of life science and medical science. This paper reviewed the latest progress about γH2AX in terms of molecular mechanism of phosphorylation/dephosphorylation, development of testing technologies, and the related applications.
