Effect of integrated traditional Chinese and western medicine on clinical efficacy and quality ;of life of the patients with early diabetic nephropathy
10.3760/cma.j.issn.1673-4246.2016.08.009
- VernacularTitle:自拟滋肾方结合西医常规疗法辅助健康教育对早期糖尿病肾病患者生活质量的影响
- Author:
Xiaolei YU
;
Jingjing WANG
;
Qianxia CHU
;
Naichao LIANG
;
Miao LI
;
Wei TONG
;
Bing LENG
- Publication Type:Journal Article
- Keywords:
Diabetic nephropathies;
Quality of life;
Integrated Chinese traditional and western medicine therapy;
Health education
- From:
International Journal of Traditional Chinese Medicine
2016;38(8):701-704
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of the self-made Zishen decoction combined with conventional western medicine therapy and health education on the patients with early diabetic nephropathy. Methods The 112 patients with DN were randomly assigned to 2 groups (each group 56 patients) at a ratio of 1:1. The control group was treated with control of glucose, blood pressure, lipid, and diet therapy, and the treatment group was with self-made prescription of invigorating the kidney and health education based on the control group treatment. All patients were treated for 6 months. The SF-36 scale was used to assess the quality of life, and the clinical effect was determined based on the blood biochemical indexes. Results Total clinical effect of the treatment group was 85.7%(48/56), and the control group was 67.9%(38/56) (χ2=4.057, P=0.044). Compared with the control group after treatment for 6 months, the physical condition (72.17 ± 13.41 vs. 64.59 ± 11.83, t=3.172), social function (64.58 ± 14.54 vs. 58.94 ± 14.62, t=2.047), physical role function (55.82 ± 10.11 vs. 47.46 ± 10.18, t=4.360), emotional role function (60.43 ± 10.20 vs. 56.04 ± 11.44, t=2.143), energy (69.86 ± 11.43 vs. 62.47 ± 11.12, t=3.468), general health status (68.57 ± 11.25 vs. 62.45 ± 11.78, t=2.812) of the treatment group were significantly improved (P<0.01 or P<0.05). Conclusion The self-made Zishen decoction and health education combined with conventional western medicine can improve the clinical effect and quality of life of patients with DN.