Efficacy of combining ultrasonic with three-dimensional imaging guided microwave ablation in treating large hepatocellular carcinoma: a comparative study
10.3760/cma.j.issn.1007-8118.2016.08.002
- VernacularTitle:超声联合三维影像技术在微波消融治疗大肝癌中的应用
- Author:
Wenfeng SHEN
;
Zhiqiang FENG
;
Hongyi ZHANG
;
Yufeng ZOU
;
Xinhui LI
;
Mei XIAO
;
Gang ZHAO
- Publication Type:Journal Article
- Keywords:
Ultrasonic;
Three-dimensional imaging;
Microwave ablation;
Large hepatocellular carcinoma;
Transcatheter arterial chemoembolization
- From:
Chinese Journal of Hepatobiliary Surgery
2016;22(8):509-512
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficacy of combining ultrasonic with three-dimensional imaging guided microwave ablation in treating large hepatocellular carcinoma.Method The clinical data of 262 patients with large unresectable liver cancer who were admitted to the Air Force General Hospital from Jan 2011 to Jun 2014 were retrospectively analyzed.Of these patients,136 underwent transcatheter arterial chemoembolization (TACE),and the remaining 126 patients underwent combined ultrasonic with three-dimensional imaging guided microwave ablation (MWA).The AFP levels,tumor ablation rate,postoperative complication rates and survival rates between the two groups were compared.Result There were significant differences in the AFP levels in the two groups before and after surgery (P ＜0.05),but no significant differences were found between the 2 groups (P ＞ 0.05).A significant difference was also observed on tumor ablation rate.In the MWA group,11 patients (8.73％) developed complications,while 21 patients (15.44％) in the TACE group developed complications,(P ＜ 0.05).The 3-month,9-month,1-year,2-year and 3-year survival rates were 99％,95％,81％,70％ and 57％ in the MWA group,and 98％,94％,63％,36％ and 28％ in the TACE group.There were significant differences in the 1-year,2-year and 3-year survival rates,but no significant difference were observed in the 3-month and 9-month survival rates.Conclnsion Combined ultrasonic with three-dimensional imaging guided microwave ablation increased the rate of tumor ablation and prolonged the survival time of patients with large hepatocellular carcinoma.
