Advances in imaging and pathological research on extramural vascular invasion of rectal cancer
10.3760/cma.j.issn.1673-9752.2016.08.018
- VernacularTitle:直肠癌壁外血管侵犯影像学及相关病理学研究进展
- Author:
Xun YAO
;
Yi WANG
- Publication Type:Journal Article
- Keywords:
Rectal neoplasms;
Extramural vascular invasion;
Magnetic Resonance Imaging
- From:
Chinese Journal of Digestive Surgery
2016;15(8):847-850
- CountryChina
- Language:Chinese
-
Abstract:
Extramural vascular invasion(EMVI)was defined as the presence of tumor cells within an endotheliumlined vessel beyond the muscularis propria.High-resolution MRI had 100％sensitivity and 89％specificity in identification of large(caliber greater than 3 mm)EMVI with histopathology as reference.EMVI detected by both histopathology and MRI was significantly associated with local recurrence,distance metastasis and tumor-related death in rectal cancer,which was also identified as an independent prognostic factor for 3-year tumor-free survival and overall survival.EMVI could be used as one of the risk factors,which would allow stratification of patients with rectal cancer to receive neoadjuvant chemoradiotherapy(neoCRT).Moreover,EMVI detected by high-resolution MRI was identified as an independent predictor for response to neoCRT.Tumor regression grading scale defined by high-resolution MRI could be used to evaluate EMVI regression after neoCRT.
