Safety and efficacy of ligasure vessel sealing system for thyroidectomy: a Meta analysis

VernacularTitle:Ligasure血管闭合系统在甲状腺切除术中安全性和有效性的Meta分析
Author: Lianshun LI ; Jie YANG ; Zankai WU ; Zuoyi JIAO
Publication Type:Journal Article
Keywords: Thyroid surgery; Ligasure vessel sealing system; Hypocalcaemia; Recurrent laryneal nerve
From: Chinese Journal of Endocrine Surgery 2016;10(4):307-312
CountryChina
Language:Chinese
Abstract: Objective To evaluate the safety and efficacy of ligasure vessel sealing system (LVSS) and conventional ligation haemostasis in thyroidectomy.Methods Pubmed,EMBASE,Medline,and CNKI were performed to search for randomized controlled trial.Literature selection and data collection were completed by 2 researchers independently.The assessment of methodological quality was conducted with Cochrane Handbook 5.1.The Review Manager software 5.2 was used for Meta analysis.Results A total of 11 studies (934 patients) were involved.Meta-analysis indicated that the operation time was shorter in LVSS group [WMD=-12.47,95％ CI (-18.33,-6.61),P＜0.0001].No significant difference was found in intra-operative blood loss,incidence of hypocalcaemia,recurrent laryngeal nerve (RLN) injury,or hospitalization time between the 2 groups (P＞0.05).Conclusion LVSS can reduce the operation time without increasing intra-operative blood loss,incidence of hypocalcemia,RLN injury,or hospitalization time,which is a safe and effective haemostasis method.