Research progress of the relation between A20 and cancers
10.3760/cma.j.issn.1674-6090.2016.04.018
- VernacularTitle:锌指蛋白A20与恶性肿瘤关系的研究进展
- Author:
Yaoqi WANG
;
Xianying MENG
;
Guang CHEN
;
Qiang ZHANG
;
Jiabin HAN
- Publication Type:Journal Article
- Keywords:
Cancer;
Zinc finger protein A20;
Tumor necrosis factor alpha-induced protein 3
- From:
Chinese Journal of Endocrine Surgery
2016;10(4):333-335
- CountryChina
- Language:Chinese
-
Abstract:
The zinc finger protein A20 exists in many kinds of ceils in the body and plays multiple roles in physiological and pathological processes such as regulation of immune response,inflammatory diseases and cancers by inhibiting cell apoptosis induced by tumor necrosis factor (TNF) and restricting NFKB signaling pathway.Recently,the role of A20 in generation and development of tumors draws wide attention,hence,we summarized recent research progress of the relation between A20 and cancer in this review.