Value of 99Tcm-MIBI tomography and registration with integrated CT in preoperative localization and diagnosis of secondary hyperparathyroidism
10.3760/cma.j.issn.1674-6090.2016.01.006
- VernacularTitle:99Tcm-MIBI断层及同机CT融合显像在继发性甲状旁腺功能亢进症术前定位诊断中的价值
- Author:
Changming ZHANG
;
Huan MA
;
Yufang ZHANG
- Publication Type:Journal Article
- Keywords:
Secondary hyperparathyroidism;
Technetium(99TcM)methoxy isobutyl isonitrile;
Single photon emission computed tomography;
Fusion imaging
- From:
Chinese Journal of Endocrine Surgery
2016;10(1):23-25
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the value of technetium-99m methoxy isobutyl isonitrile (99Tcm-MIBI)tomography and integrated CT in preoperative localization diagnosis of secondary hyperparathyroidism (SHPT).Methods 28 patients with SHPT were selected.15 minutes and 90 minutes (delayed images)after intravenous administration of 99Tcm-MIBI 370 MBq,static anterior planar images of the neck and chest were obtained.99Tcm-MIBI tomography and integrated CT scan were acquired after the delayed imaging.The imaging findings were compared to the pathological results.Results The detection rate of SHPT lesions by 99Tcm-MIBI dua-phase imaging and 99Tcm-MIBI tomography and registration with integrated CT scan was 53.3% and 70.7% respectively.The difference had statistical significance(X2 =5.903,P<0.05).The fusion imaging with integrated CT can provide detailed anatomy data and more information for surgical doctors.Conclusion 99Tcm-MIBI tomography and registration with integrated CT scan can improve the detection rate of SHPT compared with 99Tcm-MIBI dua-phase imaging,provide more detailed anatomy data,and has high clinical value in preoperative localization and diagnosis of SHPT.