PI3K signaling pathway in colorectal cancer
10.3760/cma.j.issn.1673-422X.2016.08.018
- VernacularTitle:PI3K信号通路在结直肠癌中的作用
- Author:
Hao WANG
;
Qingling ZHANG
- Publication Type:Journal Article
- Keywords:
Colorectal neoplasms;
1-Phosphatidylinositol 3-kinase;
Signal transduction;
Drug therapy
- From:
Journal of International Oncology
2016;43(8):631-633
- CountryChina
- Language:Chinese
-
Abstract:
Since the early symptoms are very hidden,most of patients with colorectal cancer (CRC)have occurred metastasis when diagnosed.Recently,chemotherapy combined with targeted therapy is the major therapeutic strategy for metastatic CRC and the high frequency activation of phosphatidylinositol 3-kinase (PI3K) signaling pathway has been validated sharing a close relationship with the development of CRC,contributing important values for the diagnosis and therapy of CRC.
