The possible mechanism of the relationship between adiponectin and intracranial atherosclerosis
10.3760/cma.j.issn.1673-4165.2016.06.014
- VernacularTitle:脂联素与颅内动脉粥样硬化的关系及其可能机制
- Author:
Manman XU
;
Yun XU
;
Jingwei LI
- Publication Type:Journal Article
- Keywords:
Adiponectin;
Intracranial Arteriosclerosis;
Stroke;
Brain Ischemia;
Diabetes Mellitus;
Metabolic Syndrome X;
Hyperlipidemias;
Inflammation;
Risk Factors;
Biomarkers
- From:
International Journal of Cerebrovascular Diseases
2016;24(6):561-564
- CountryChina
- Language:Chinese
-
Abstract:
Different from Westerners,intracranial atherosclerosis (ICAS) is a main cause for acute ischemic stroke in Eastern population.Studies have shown that ICAS is associated with the risk factors including metabolic syndrome,dyslipidemia,diabetes mellitus,and inflammation.Adiponectin is involved in oxidative stress and glycolipid metabolism,its reduced level is the most important risk factor for metabolic syndrome and the most prominent inflammatory markers.Numerous studies have suggested that adiponectin is associated with cardiovascular diseases,and it is used as a preventive marker.In recent years,the relationship between adiponectin and ICAS has become a hot research topic.This article mainly reviews the roles of adiponectin in ICAS.
