Role of epigenetic regulation in cerebral ischemia
10.3760/cma.j.issn.1673-4165.2016.04.012
- VernacularTitle:表观遗传调控在脑缺血中的作用
- Author:
Xinyu LI
;
Lixuan ZHAN
;
Long LONG
;
En XU
- Publication Type:Journal Article
- Keywords:
Brain Ischemia;
Epigenesis,Genetic;
DNA Methylation;
Histone Demethylases;
MicroRNAs;
RNA,Long Noncoding;
Gene Expression Regulation
- From:
International Journal of Cerebrovascular Diseases
2016;24(4):371-377
- CountryChina
- Language:Chinese
-
Abstract:
The interaction between genetic and environmental factors influences the onset,development and prognosis of cerebral ischemia.Recently,epigenetic regulation is increasingly becoming a research focus on cerebral ischemia,and there has been great progress in research on DNA methylation,histone modification and miRNA network.Epigenetic regulation provides a new idea for identifying potential therapeutic targets of cerebral ischemia.