Effects of sevoflurane on right ventricular function after cardiopulmonary bypass in patients undergoing coronary artery bypass grafting
- VernacularTitle:七氟醚对冠状动脉旁路移植术患者心肺转流后右心室功能的影响
- Author:
Zhonghua LUO
;
Hongwei SHI
;
Yamei ZHAO
;
Zhenhong WANG
;
Yali GE
;
Haiyan WEI
;
Hongguang BAO
- Publication Type:Journal Article
- Keywords:
Coronary artery bypass;
Cardiopulmonary bypass;
Right ventricular function
- From:
The Journal of Clinical Anesthesiology
2016;32(9):837-840
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effects of sevoflurane on right ventricular systolic function after cardiopulmonary bypass in patients undergoing coronary artery bypass grafting(CABG). Methods Eighteen patients with coronary heart disease,13 males,5 females,ASA Ⅱ or Ⅲ,aged 50-80 years,measuring 1 50-182 cm in height,weighing 5 1-96 kg,scheduled for CABG under CPB were enrolled in this study.Anesthesia was maintained with intravenous anesthesia, and 1 MAC sevoflurane inhalation lasted for 60 min after CPB.Hemodynamic indicators such as HR,MAP, CVP,cardiac output (CO),Systemic vascular resistance (SVR)and right ventricular parameters in-cluding tricuspid annular plane systolic excursion (TAPSE)and velocity (TAPSV)were recorded be-fore sternotomy (T2 ),30 min after CPB (T3 ),60 min after CPB (T4 ).Results Compared with T1 , CO was increased at T2 (P <0.05);compared with T2 ,CO was decreased at T3 and T4 (P <0.05 or P <0.01),with a statistical significance;compared with T1 ,TAPSE and TAPSV were increased at T2 (P <0.05 or P <0.01);compared with T2 ,TAPSE and TAPSV were decreased at T3 and T4 (P<0.05);with a statistical significance in TAPSE and TAPSV.Conclusion For the patients undergo-ing CABG under CPB,1 MAC sevoflurane inhalation after CPB can reduce right ventricular systolic function,which,however,is within the normal ranges.
