Observation on the clinical application of target-controlled infusion of propofol guided by Narcotrend for anesthetic induction in renal transplantation patients
- VernacularTitle:Narcotrend 监测下丙泊酚靶控输注技术在肾移植患者全麻诱导期的应用
- Author:
Wenlong YAN
;
Shuhua SHU
;
Di WANG
;
Yali GAO
;
Xin WEI
;
Xiaoqing CHAI
- Publication Type:Journal Article
- Keywords:
Kidney transplantation;
Target-controlled infusion;
Anesthesia induction;
Propofol;
Stress response
- From:
The Journal of Clinical Anesthesiology
2016;32(9):841-844
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the hemodynamic change and stress reaction of target-con-trolled infusion (TCI)of propofol guided by Narcotrend for anesthetic induction in renal transplanta-tion patients.Methods Forty patients (25 males,1 5 females,aged 21-38 years,ASA grade Ⅲ orⅣ)undergoing related living donor kidney transplantation were randomly divided into two groups:group A and group B (n =20).Group A was induced using TCI system with propofol under the moni-toring of Narcotrend.Group B was induced with propofol manually.HR,MAP,Narcotrend index (NTI),blood glucose (Glu)and plasma cortisol (Cor)were measured before induction (T0 ),before tracheal intubation (T1 ),and 1 (T2 ),3 (T3 ),and 5 (T4 )minutes afterwards.Results HR and MAP at T1 were lower than those at T0 (P < 0.05 )in two groups,they were significantly lower in group B than in group A at corresponding points(P <0.05).HR and MAP in group B increased sig-nificantly (P <0.05)and were significantly higher than those in group A (P <0.05)at T2 and T3 . There was no obvious difference in Glu and Cor between T0 and T2-T4 in group A.Glu and Cor at T2-T4 were obviously higher than those at T0 (P <0.05)in group B and those at corresponding points in group A (P <0.05).Conclusion TCI of propofol guided by Narcotrend in renal transplantation pa-tients can better control the depth of anesthesia,attenuate the stress reaction caused by tracheal intu-bation,and keep hemodynamic smooth during anesthesia induction.
