Long non-coding RNA in digestive system tumors
- VernacularTitle:长非编码 RNA 在消化系统肿瘤中的研究进展
- Author:
Lei PAN
;
Wei LIANG
;
Min FU
;
Hui QIAN
;
Wenrong XU
;
Pengcheng JIANG
;
Xu ZHANG
- Publication Type:Journal Article
- Keywords:
Digestive system neoplasms;
Tumor markers,biological;
Long noncoding RNA
- From:
Journal of International Oncology
2016;43(9):706-710
- CountryChina
- Language:Chinese
-
Abstract:
Long noncoding RNA (lncRNA) is a class of RNA molecules that longer than 200 nucleotides.lncRNA is lack of functional open reading frames and has no protein coding ability.Recently, accumulating evidences indicate that lncRNA plays active roles in tumor carcinogenesis and progression.The aberrant expression of lncRNA is significantly correlated with the growth,metastasis,and therapy-resistance of digestive system tumors.Thus,lncRNA may be served as new targets for the diagnosis,treatment,and progno-sis of patients with digestive system tumors.
