Clinical Features in Patients With Hypertrophic Cardiomyopathy Combining Left Ventricular Apical Aneurysm
10.3969/j.issn.1000-3614.2016.07.014
- VernacularTitle:肥厚型心肌病合并左心室心尖部室壁瘤患者的临床特征
- Author:
Hua LI
;
Chaowu YAN
;
Zhongying XU
;
Jianrong LI
;
Hong MENG
;
Hao WANG
;
Jiejing SUN
;
Jianhua LV
;
Qiong LIU
- Publication Type:Journal Article
- Keywords:
Cardiomyopathy,hypertrophic;
Heart aneurysm;
Disease attributes
- From:
Chinese Circulation Journal
2016;31(7):679-682
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To analyze the clinical features in patients with hypertrophic cardiomyopathy (HCM) combining left ventricular apical aneurysm (LVAA) . Methods: A total of 1194 HCM patients treated in our hospital from 2007-01 to 2013-01 were studied. There were 23 (1.93%) patients combining with LVAA including 19 male and 4 female; coronary artery disease (CAD) was excluded and the patients received echocardiography and coronary angiography (CAG) examinations. Results: There were 21/23 LVAA patients having left mid-ventricular obstruction and 7 of them combining simultaneous left ventricular outflow obstruction.The average pressure gradient in those 21 patients was (56.8 ± 12.9) mmHg and the rest 2 patients suffered from apical hypertrophic cardiomyopathy.The mean maximum thickness of left ventricular wall was (21.8 ± 6.3) mm and the dimension of left ventricle was (39.4 ± 5.2) mm. Electrocardiography showed that 3 patients had paroxysmal ventricular tachycardia;CAG indicated that 6 patients combined with coronary artery muscular bridge at left anterior descending (LAD) artery. The patients were followed-up for (2.7 ± 1.3) years and adverse cardiovascular events occurred in 5 patients during that period. Conclusion: HCM combining LVAA was most frequently happened in patients with left mid-ventricular hypertrophic cardiomyopathy, some of them combining simultaneous left ventricular outflow obstruction and had the higher occurrence rate of adverse cardiovascular events. Early and accurate diagnosis is very important for guiding clinical treatment.
