Polyunsaturated fatty acids in regulation of tumor angiogenesis:research progress
10.3867/j.issn.1000-3002.2016.07.013
- VernacularTitle:多不饱和脂肪酸对肿瘤血管生成作用的研究进展
- Author:
Pengkun WANG
;
Ziling WANG
- Publication Type:Journal Article
- Keywords:
polyunsaturated fatty acids;
tumor;
angiogenesis
- From:
Chinese Journal of Pharmacology and Toxicology
2016;30(7):790-796
- CountryChina
- Language:Chinese
-
Abstract:
Polyunsaturated fatty acids (PUFAs) are important structural fatty acids of biological membrane. They play important roles in regulation of lipid metabolism,stimulation of growth and development,protection a gainst cancer,retardation of aging,immuno-regulation, cardiovascular health,and bodymass loss. In recent years, researchers have found t hat ω-6 PUFAs can promote tumor angiogenesis,while ω-3 PUFAs have the properties of inhibiting tumor angiogenesis. This review focuses on the effects of these two types of fatty acids on tumors,especially on the regulation of tumor angiogenesis.
