Predictive Value of hs-CRP Level in Patients With Persistent Atrial Fibrillation Recurrence After Radiofrequency Catheter Ablation
10.3969/j.issn.1000-3614.2016.07.010
- VernacularTitle:高敏C反应蛋白对持续性心房颤动患者射频消融术后复发的预测价值
- Author:
Peng DUAN
;
Xiaojing LIU
;
Yang LI
;
Qinglei ZHU
- Publication Type:Journal Article
- Keywords:
C-reactive protein;
Atrial fibrillation;
Catheter ablation
- From:
Chinese Circulation Journal
2016;31(7):664-667
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the predictive value of high-sensitivity C-reactive protein (hs-CRP) levels in patients with persistent atrial fibrillation (AF) recurrence after radiofrequency catheter ablation (RFCA). Methods: A total of 77 patients of persistent AF as the first diagnosis with initial RFCA in our hospital were studied. The patients were divided into 2 groups: Recurrent group, n=27 and Non recurrent group, n=50. Basic clinical conditions were studied by Cox model analysis to screen the risk factors for AF recurrence, receiver operating characteristic (ROC) curve was conducted to assess the predictive value of hs-CRP level on AF recurrence. Results: AF recurrence was related tothe age (HR=1.126, 95% CI 1.044-1.215, P=0.002), body mass index (HR=1.297, 95% CI 1.077-1.563, P=0.006), hypertension at stage II (HR=4.142, 95% CI 1.047-16.390, P=0.043), hypertension at stage III (HR=8.595, 95%CI 1.913-38.610, P=0.005), left atrial size (HR=1.438, 95% CI 1.212-1.707, P=0.000) and hs-CRP (HR=2.026, 95% CI 1.010-4.061,P=0.047). The area under ROC curve of hs-CRP level was 0.693,P=0.005 with the cut-off point at 0.355 mg/dl. Conclusion: Persistent AF recurrence after RFCA was related to pre-operative inflammatory status; actively control pre-operative condition may reduceAF recurrence, improve prognosis and decrease adverse cardiovascular event in relevant patients.
