Research progress of relation between Hippo-YAP signaling pathway and tumor
10.3760/cma.j.issn.1006-9801.2016.06.019
- VernacularTitle:Hippo-YAP信号通路与肿瘤关系的研究进展
- Author:
Daosheng LI
- Publication Type:Journal Article
- Keywords:
Tumor;
Hippo signaling pathway;
YAP protein
- From:
Cancer Research and Clinic
2016;28(6):429-432
- CountryChina
- Language:Chinese
-
Abstract:
The Hippo-YAP signaling pathway,an important signaling pathway of tumor suppressor,is featured by functions of adjusting the organ size and maintaining the dynamic balance between cell proliferation and apoptosis.Several researches have revealed that the Hippo-YAP signaling pathway can affect cell proliferation and apoptosis so as to participate in the development of tumor.This paper will review the effect and mechanism of Hippo-YAP signaling pathway in tumor.
